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Most reports of clinically sizeable drug interactions occurring with the barbiturates have involved phenobarbital. Nevertheless, the appliance of those information to other barbiturates seems valid and warrants serial blood level determinations with the applicable drugs when there are numerous therapies.A: The capsules is usually opened and place i
In clients with hepatic damage, barbiturates should be administered with caution and originally in decreased doses. Barbiturates shouldn't be administered to individuals displaying the premonitory indications of hepatic coma.Anticoagulants. Phenobarbital lowers the plasma levels of dicumarol and causes a decrease in anticoagulant activity as measur